CURRICULUM VITAE

• IDENTICAL INFORMATION

  Name:

  Takaoki Kasahara

  e-mail:

  casa@brain.riken.jp

  takaoki@gmail.com

  Lab address:

  Laboratory for Molecular Dynamics of Mental Disorders,
  RIKEN Brain Science Institute
  2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan
  

  Web sites:

  http://www.kaorin.net/

  http://www.brain.riken.jp/labs/mdmd/

• EDUCATION

  1991

  Graduated from Fujishima High School (Fukui)

  1996

  Bachelor of Arts and Sciences, The University of Tokyo

  1998

  Master of Arts and Sciences,
  Graduate School of Arts and Sciences, The University of Tokyo

  2001

  Ph.D., Graduate School of Science, The University of Tokyo

• PERSONAL INFORMATION

  Birth Date: September 23, 1972
  Birth Place: Fukui, Japan
  Citizenship: Japan
  

• EMPLOYMENT

  April, 2007 - present

  Deputy team leader, RIKEN Brain Science Institute

  April, 2006 - March, 2007

  Research scientist, RIKEN Brain Science Institute

  April, 2003 - March, 2006

  Special Postdoctoral Researcher, RIKEN

  April, 2001 - March, 2003

  Research scientist, RIKEN Brain Science Institute

  April, 1998 - March, 2001

  JSPS Research fellow (DC1)
  

• AWARDS AND HONORS
  
  
  • Research Award, Japanese Society of Biological Psychiatry (2007)
  • Ando Momofuku Prize, ANDO Foundation (2003)
  • Fellowship of the Special Postdoctoral Researchers Program, RIKEN [April, 2003 - March, 2006]
  • Fellowship of the Japan Society for the Promotion of Science for Young Scientists (DC1) [April, 1998 - March, 2001]
  • Scholarship from The Japan Scholarship Foundation [April, 1996 - March, 1998]
  
  
• PUBLICATIONS
  
  
  1. Kubota, M., Kasahara, T., Nakamura, T., Ishiwata, M., Miyauchi, T. and Kato, T. (2006) Abnormal Ca²⁺ dynamics in transgenic mice with neuron-specific mitochondrial DNA defects. J. Neurosci. 26, 12314-12324.
  2. Kasahara, T., Kubota, M., Miyauchi, T., Noda, Y., Mouri, A., Nabeshima, T. and Kato, T. (2006) Mice with neuron-specific accumulation of mitochondrial DNA mutations show mood disorder-like phenotypes. Mol. Psychiatry 11, 577-593. [Image]
  3. Kakiuchi, C., Iwamoto, K., Ishiwata, M., Bundo, M., Kasahara, T., Kusumi, I., Tsujita, T., Okazaki, Y., Nanko, S., Kunugi, H., Sasaki, T. and Kato, T. (2003) Impaired feedback regulation of XBP1 as a genetic risk factor of bipolar disorder. Nat. Genet. 35, 171-175.
  4. Kasahara, T. and Kato, T. (2003) A new redox-cofactor vitamin for mammals. Nature 422, 832.
  5. Kasahara, T., Okano, T., Haga, T. and Fukada, Y. (2002) Opsin-G₁₁-mediated signaling pathway for photic entrainment of the chicken pineal circadian clock. J. Neurosci. 22, 7321-7325.
  6. Okano, T., Yamamoto, K., Okano, K., Hirota, T., Kasahara, T., Sasaki, M., Takanaka, Y. and Fukada, Y. (2001) Chicken pineal clock genes: implication of BMAL2 as a bidirectional regulator in circadian clock oscillation. Genes Cells 6, 825-836.
  7. Hirota, T., Kagiwada, S., Kasahara, T., Okano, T., Murata, M., and Fukada, Y. Effect of brefeldin A on melatonin secretion of chick pineal cells. J. Biochem. 129, 51-59.
  8. Kasahara, T., Okano, T., Yoshikawa, T., Yamazaki, K. and Fukada, Y. (2000) Rod-type transducin a-subunit mediates a phototransduction pathway in the chicken pineal gland. J. Neurochem. 75, 217-224.
  9. Matsushita, A., Yoshikawa, T., Okano, T., Kasahara, T. and Fukada, Y. (2000) Colocalization of pinopsin with two types of G-protein a-subunits in the chick pineal gland. Cell Tissue Res. 299, 245-251.
  10. Okano, T., Yamazaki, K., Kasahara, T. and Fukada, Y. (1997) Molecular cloning of heterotrimeric G-protein a-subunits in chicken pineal gland. J. Mol. Evol. 44, S91-97.
  
  [Brief Notes and Reviews]
  
  1. Kato ,T., Kubota, M. and Kasahara, T. (2006) Animal models of bipolar disorder. Neurosci. Biobehav. Rev. (in press).
  2. Kasahara, T. and Kato, T. (2005) Nature 433, E11-E12.
  
  [Japanese]
  
  1. Kato ,T. and Kasahara, T. (2006) Animal model for bipolar disorder. Jap. J. Mol. Psychiarty 6, 405-410.
  2. Kasahara, T. (2006) Metabolism of PQQ, in Handbook of data for nutrition and food science, Dobunshoin, Tokyo, Japan.
  3. Kato ,T., Kakiuchi, C., Hayashi, A. and Kasahara, T. (2005) Pathological significance of endoplasmic reticulum stress in bipolar disorder. Exp. Med. 23, 2795-2798.
  4. Kasahara, T. (2004) PQQ binding motif. Seikagaku 76, 1582.
  5. Kasahara, T. and Kato, T. (2004) A mammalian enzyme utilizing pyrroloquinoline quinone as a redox cofactor. Chemistry Chem. Industry 57, 239-241.
  6. Kasahara, T. and Kato, T. (2004) Pyrroloquinoline quinone. J. Med. Technol. 48, 104-106
  7. Kato ,T. and Kasahara, T. (2004) Identification of a mammalian enzyme utilizing pyrroloquinoline quinone as its cofactor. BRAIN Techno-news 99, 22-25.
  8. Kasahara, T. (2003) New vitamin on the complex. Look Japan 49, 27.
  9. Kasahara, T. and Kato, T. (2003) Fourteenth vitamin, pyrroloquinoline quinone. Jap. J. Cli. Nutr. 103, 813-817.
  10. Kato, T. and Kasahara, T. (2003) A novel vitamin: pyrroloquinoline quinone (PQQ). Med. Technol. 31, 1266-1267.
  11. Kasahara, T. and Kato, T. (2003) Pyrroloquinoline quinone: a new vitamin for mammals. J. Cli. Exp. Med. 203, 228-229.
  12. Kasahara, T. (2003) PQQ, pyrroloquinoline quinone, is coming to a new vitamin. Tabemono Tsushin 389, 18-19.
  13. Kasahara, T. (2001) The one hundred wonders of light and colors. Tokyo Shoseki Co.,Ltd., Tokyo, Japan (co-author).
  14. Kasahara, T. and Okano, T. (1999) Visualizing of the circadian phase of clock cells. Bioimaging 7, 221-226.
  15. Fukada, Y. and Kasahara, T. (1999) Pinopsin, an extraretinal photopigment, in phototransductions (Hasunuma, Kimura, Tokunaga, ed.), pp.146-151. Springer-Verlag Tokyo, Inc., Tokyo, Japan.